B12 and Chronic Disease: Depression

Summary: There is evidence that depression is often related to B12 deficiency. Some evidence suggests B12 deficiency can be confined to the brain. In such cases, massive doses of methylcobalamin might be necessary to replete B12 stores in the brain.

I have not had a chance to research this subject in detail. However, Syd Baumel, a vegan activist and science writer from Winnipeg, Canada, has done so. Click here to open, in a new window, Syd's article, A Shot in Time Saves Mind: Vitamin B12 and Depression."